Meta-Analysis
Results from randomised controlled trials of dipyridamole, given with or without ASA, for secondary prevention after ischaemic stroke or transient ischaemic attack (TIA) have given conflicting results. A meta-analysis using individual patient data from relevant randomised controlled trials was performed. Randomised controlled trials involving dipyridamole in patients with previous ischaemic stroke or TIA were sought from searches of the Cochrane Library, other electronic databases, references lists, earlier reviews, and contact with the manufacturer of dipyridamole. Individual patient data were merged from 5 of 7 relevant trials involving 11,459 patients. Results were adjusted for age, gender, qualifying event, and history of previous hypertension.
References
Leonardi-Bee et al. Stroke 2005; 36 (1): 162-168.
PubMed Abstract
