ESPRIT (European/Australasian Stroke Prevention in Reversible Ischaemia Trial)
Results
Meta-analysis
A meta-analysis in patients with cerebral ischaemia of presumed arterial origin for the composite outcome of vascular death, nonfatal stroke, or nonfatal myocardial infarction was done. The meta-analysis is based on the data of 6 trials, including 3,888 patients allocated to DP + ASA and 3,907 to ASA alone; the total number of outcome events is 1,158.
Addition of the ESPRIT data to the meta-analysis of previous trials resulted in an overall risk ratio for the composite of vascular death, stroke, or myocardial infarction of 0.82 (95% CI 0·74–0.91).
Meta-analysis
